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N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine

Catalog No. T60231 CAS 58315-38-1

N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine is a biologically active compound belonging to the piperazine group. It is an important synthetic intermediate used in the preparation of a wide range of drugs, agrochemicals and other chemicals. It is considered an inhibitor of certain enzymes involved in drug metabolism, such as cytochrome P450 enzymes, and has also been shown to have anti-inflammatory and antitumor effects.

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N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine Chemical Structure

N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine, CAS 58315-38-1

Pack Size	Availability	Price/USD
5 mg	In stock	$ 50.00
10 mg	In stock	$ 75.00
25 mg	In stock	$ 128.00
50 mg	In stock	$ 192.00
100 mg	In stock	$ 287.00
200 mg	In stock	$ 431.00
500 mg	In stock	$ 713.00
1 mL * 10 mM (in DMSO)	In stock	$ 63.00

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Purity: 99.94%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	275.23
Formula	C11H12F3N3O2
CAS No.	58315-38-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 60 mg/mL (218 mM)

References and Literature

1. Rejmund M, et al. Piperazinyl fragment improves anticancer activity of Triapine. PLoS One. 2018 Apr 13;13(4):e0188767.

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

N-[2-nitro-4-(trifluoromethyl)phenyl]piperazine 58315-38-1 Others N[2NITRO4(TRIFLUOROMETHYL)PHENYL]PIPERAZINE inhibitor inhibit

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