Powder: -20°C for 3 years | In solvent: -80°C for 1 year
m-PEG4-Boc is a cleavable 4-unit polyethylene glycol (PEG) linker, widely employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, m-PEG4-Boc serves as a PEG-based PROTAC linker, enabling its utilization in the synthesis of PROTACs [2].
Pack Size | Availability | Price/USD | Quantity |
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100 mg | 5 days | Inquiry | |
500 mg | 5 days | Inquiry |
Description | m-PEG4-Boc is a cleavable 4-unit polyethylene glycol (PEG) linker, widely employed in the synthesis of antibody-drug conjugates (ADCs) [1]. Additionally, m-PEG4-Boc serves as a PEG-based PROTAC linker, enabling its utilization in the synthesis of PROTACs [2]. |
In vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 292.37 |
Formula | C14H28O6 |
CAS No. | 883554-11-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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