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Zolamide

Catalog No. T21281 CAS 14949-00-9

Synonyms: CL 5343, Tio-urasin, 5-Amino-TDSNH2

Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.

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Zolamide, CAS 14949-00-9

Pack Size	Availability	Price/USD
2 mg	In stock	$ 50.00
5 mg	In stock	$ 68.00
10 mg	In stock	$ 98.00
25 mg	In stock	$ 176.00
50 mg	In stock	$ 252.00

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Purity: 99.75%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.

Synonyms	CL 5343, Tio-urasin, 5-Amino-TDSNH2
Molecular Weight	180.21
Formula	C2H4N4O2S2
CAS No.	14949-00-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (277.45 mM)

References and Literature

1. Van Berkel MA, Elefritz JL. Evaluating off-label uses of acetazolamide. Am J Health Syst Pharm. 2018 Apr 15;75(8):524-531. doi: 10.2146/ajhp170279. Review. PubMed PMID: 29626002. 2. Arenas-García JI, Herrera-Ruiz D, Morales-Rojas H, Höpfl H. Interrelation of the dissolution behavior and solid-state features of acetazolamide cocrystals. Eur J Pharm Sci. 2017 Jan 1;96:299-308. doi: 10.1016/j.ejps.2016.09.025. Epub 2016 Sep 17. PubMed PMID: 27650458. 3. Llovet-Rausell A, Ruiz Tolosa F, Kudsieh B. Severe ocular side effects with acetazolamide: case report. Arch Soc Esp Oftalmol. 2016 Nov;91(11):543-546. doi: 10.1016/j.oftal.2016.03.013. Epub 2016 May 11. English, Spanish. PubMed PMID: 27179669. 4. Al-Saleem AI, Al-Jobair AM. Possible association between acetazolamide administration during pregnancy and multiple congenital malformations. Drug Des Devel Ther. 2016 Apr 15;10:1471-6. doi: 10.2147/DDDT.S99561. eCollection 2016. PubMed PMID: 27143854; PubMed Central PMCID: PMC4841426.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max Bioactive Compound Library NO PAINS Compound Library

Dose Conversion

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box

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Calculator the dilution required to prepare a stock solution

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The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Molecule Formula

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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Zolamide 14949-00-9 Others CL 5343 Tio-urasin CL-5343 5-Amino-TDSNH2 CL5343 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.