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Zafirlukast

Catalog No. T6736   CAS 107753-78-6
Synonyms: Vanticon, ICI 204219, Accolate

Zafirlukast (ICI 204219) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma.

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Zafirlukast Chemical Structure
Zafirlukast, CAS 107753-78-6
Pack Size Availability Price/USD Quantity
25 mg In stock $ 41.00
50 mg In stock $ 58.00
100 mg In stock $ 84.00
200 mg In stock $ 151.00
1 mL * 10 mM (in DMSO) In stock $ 59.00
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Purity: 99%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Zafirlukast (ICI 204219) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma.
Synonyms Vanticon, ICI 204219, Accolate
Molecular Weight 575.68
Formula C31H33N3O6S
CAS No. 107753-78-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (95.54 mM)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

H2O: < 1 mg/mL (insoluble or slightly soluble)

TargetMolReferences and Literature

1. Kassahun K, et al. Chem Res Toxicol,2005, 18(9), 1427-1437. 2. Mahgoub AA, et al. Toxicol Lett,2003, 145(1), 79-87. 3. Capoci I R G, Faria D R, Sakita K M, et al. Repurposing approach identifies new treatment options for invasive fungal disease[J]. Bioorganic chemistry. 2019 Mar;84:87-97.

TargetMolCitations

1. Capoci I R G, Faria D R, Sakita K M, et al. Repurposing approach identifies new treatment options for invasive fungal disease. Bioorganic Chemistry. 2019 Mar;84:87-97 2. Zhang S, Gao C, Das T, et al. The spike-ACE2 binding assay: An in vitro platform for evaluating vaccination efficacy and for screening SARS-CoV-2 inhibitors and neutralizing antibodies. Journal of Immunological Methods. 2022: 113244.

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library GPCR Compound Library Anti-Cancer Clinical Compound Library Inhibitor Library Anti-Cancer Approved Drug Library Membrane Protein-targeted Compound Library Anti-Cancer Drug Library Approved Drug Library Orally Active Compound Library Drug-induced Liver Injury (DILI) Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Zafirlukast 107753-78-6 GPCR/G Protein Leukotriene Receptor ICI204219 Vanticon ICI-204219 ICI 204219 Inhibitor inhibit Accolate inhibitor

 

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