Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,140.00 | |
50 mg | 10-14 weeks | $ 2,785.00 | |
100 mg | 10-14 weeks | $ 3,520.00 |
Description | VDR agonist 1 (compound 28), a nonsteroidal Vitamin D receptor (VDR) agonist, demonstrates potent activity with a low IC 50 of 690 nM in MCF-7 cells. It inhibits cell cycle progression through upregulation of p21 and p27, and induces apoptosis by elevating BAX expression while reducing Bcl-2 levels [1]. |
Targets&IC50 | VDR (MCF-7 cells):690 nM |
Molecular Weight | 509.77 |
Formula | C32H51N3O2 |
CAS No. | 2269494-43-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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VDR agonist 1 2269494-43-9 Others inhibitor inhibit