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Transdermal Peptide Disulfide Acetate

Catalog No. TP1033L CAS TP1033L

Synonyms: TD 1 (peptide) acetate, Transdermal Peptide Disulfide Acetate (888486-23-5 free base)

Transdermal Peptide acetate(888486-23-5 free base) (TD 1 (peptide) acetate) is a 11-amino acid peptide, binds toNa+/K+-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide can enhance the transdermal delivery of many macromolecules.Transdermal Peptide TD 1 Amide is novel peptide designed to enhance transdermal drug delivery.

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Transdermal Peptide Disulfide Acetate Chemical Structure

Transdermal Peptide Disulfide Acetate, CAS TP1033L

Pack Size	Availability	Price/USD
1 mg	In stock	$ 78.00
5 mg	In stock	$ 171.00
10 mg	In stock	$ 263.00
25 mg	In stock	$ 475.00
50 mg	In stock	$ 695.00
100 mg	In stock	$ 988.00
500 mg	In stock	$ 1,980.00

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Purity: 99.97%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

In vitro

In the presence of Transdermal Peptide, because of the specific binding of Transdermal Peptide to ATP1B1, cells will upregulate the level of ATP1B1 to maintain function and structure; as a result, the expression of ATP1B1 increases. However, as time goes on, some Transdermal Peptide molecules may be transported into cells by endocytosis; consequently, the expression of ATP1B1 then decreases. The interaction between Transdermal Peptide and ATP1B1 changes not only the expression of ATP1B1, but also the localization of ATP1B1 and then the structure of the epidermal layer. This interaction can be attenuated by inhibitors or competitors, which would result in the reduced delivery of macromolecular drugs across the skin[1].

Synonyms	TD 1 (peptide) acetate, Transdermal Peptide Disulfide Acetate (888486-23-5 free base)
Molecular Weight	1121.2
Formula	C42H68N14O18S2
CAS No.	TP1033L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 2.5 mM

References and Literature

1. Wang C, et al. Role of the Na(+)/K(+)-ATPase beta-subunit in peptide-mediated transdermal drug delivery. Mol Pharm. 2015 Apr 6;12(4):1259-67.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library

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Keywords

Transdermal Peptide Disulfide Acetate TP1033L Membrane transporter/Ion channel ATPase Transdermal Peptide acetate(888486235 free base) Transdermal Peptide acetate(888486 23 5 free base) TD 1 (peptide) Acetate TD 1 (peptide) acetate Transdermal Peptide Disulfide Acetate (888486-23-5 free base) inhibitor inhibit

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