Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Top1 inhibitor 1 is a potent inhibitor of human topoisomerase I (Top1)(IC50: 29 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Top1 inhibitor 1 is a potent inhibitor of human topoisomerase I (Top1)(IC50: 29 nM). |
Targets&IC50 | Topo I (human):29 nM |
In vitro | Top1 inhibitor 1 reveals cytotoxicity in cancerous cells including MCF7 with IC50 of 2.74 μM, HeLa with IC50 of 2.61 μM, HCT116 with IC50 of 2.34 μM, NIH: OVCAR-3 (IC50: 2.35 μM) cells compared to the non-cancerous cells like HEK293 (IC50: 8.34 μM) . |
Molecular Weight | 426.47 |
Formula | C24H22N6O2 |
CAS No. | 2302772-05-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Top1 inhibitor 1 2302772-05-8 Others Top-1 inhibitor 1 inhibitor inhibit