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Tauroursodeoxycholate dihydrate

Catalog No. T16998   CAS 117609-50-4
Synonyms: Taurolite dihydrate, TUDCA dihydrate, UR 906 dihydrate

Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decreases the expression of apoptosis molecules, such as caspase-3 and caspase-12.

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Tauroursodeoxycholate dihydrate Chemical Structure
Tauroursodeoxycholate dihydrate, CAS 117609-50-4
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decreases the expression of apoptosis molecules, such as caspase-3 and caspase-12.
Synonyms Taurolite dihydrate, TUDCA dihydrate, UR 906 dihydrate
Molecular Weight 535.73
Formula C26H49NO8S
CAS No. 117609-50-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 83.33 mg/mL (155.54 mM), sonification is recommended.

TargetMolReferences and Literature

1. Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCα-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16. 2. Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345.

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Keywords

Tauroursodeoxycholate dihydrate 117609-50-4 Apoptosis MAPK Proteases/Proteasome ERK Caspase Taurolite Dihydrate UR-906 Tauroursodeoxycholate Dihydrate Tauroursodeoxycholate UR906 Dihydrate TUDCA UR-906 Dihydrate UR 906 Dihydrate TUDCA Dihydrate Taurolite dihydrate UR 906 TUDCA dihydrate Taurolite UR 906 dihydrate UR906 inhibitor inhibit

 

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