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TCCP

Catalog No. T34791 CAS T34791

TCCP is a natural inducer of apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.

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TCCP, CAS T34791

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Biological Description

Chemical Properties

Storage & Solubility Information

Description

TCCP is a natural inducer of apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.

Molecular Weight	379.54
Formula	C22H37NO4
CAS No.	T34791

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Rashmi KC, Harsha Raj M, Paul M, Girish KS, Salimath BP, Aparna HS. A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity. Chem Biol Interact. 2019 Feb 1;299:120-130. doi: 10.1016/j.cbi.2018.12.005. Epub 2018 Dec 10. PubMed PMID: 30543781. 2. Rashmi KC, Atreya HS, Harsha Raj M, Salimath BP, Aparna HS. A pyrrole-based natural small molecule mitigates HSP90 expression in MDA-MB-231 cells and inhibits tumor angiogenesis in mice by inactivating HSF-1. Cell Stress Chaperones. 2017 Sep;22(5):751-766. doi: 10.1007/s12192-017-0802-0. Epub 2017 Jul 17. PubMed PMID: 28717943; PubMed Central PMCID: PMC5573693.

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Keywords

TCCP T34791 inhibitor inhibit

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