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Sulfathiazole

Name: Sulfathiazole
Brand: TargetMol
SKU: T0747
Rating: 4.5 (1 reviews)

(Synonyms: 2-Sulfanilamidothiazole) Copy Product Info

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Synonyms: 2-Sulfanilamidothiazole

Catalog No. T0747 Copy Product Info

Purity: 99.95%

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Sulfathiazole (2-Sulfanilamidothiazole), an organosulfur compound, has been served as a short-acting sulfa medicine.

Cas No. 72-14-0

Pack Size	Price	USA Stock	Global Stock	Quantity
2 g	$29	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.95%

Appearance:Solid

Color:White

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COA HPLC HNMR LCMS

Product Introduction

Bioactivity

Description	Sulfathiazole (2-Sulfanilamidothiazole), an organosulfur compound, has been served as a short-acting sulfa medicine.
In vitro	Sulfathiazole (20 μg/L) begins degrading between days 31 and 38 in one of two batch reactors with different wastewater matrices, at a faster rate than sulfamethoxazole or sulfamethazine in the nitrification process (S3). [1] Recovery from spiked manure slurry samples is 64% for Sulfathiazole at pH 9. Sulfathiazole, with a pKa of 7.1 and retention times (tR) of 7.8, shows S/N values above 100 at the 1 mg/kg level. [2] Its sorption to inorganic sorbents is pH-dependent, influenced by sorbate speciation and sorbent charge properties, with cations being most significant for clay mineral sorption, followed by neutral species. [3] Sulfathiazole possesses at least five polymorphic forms: I, II, III, IV, and V and exists in the solid state in the imido form. [4] Sulfathiazole (94.9 mg/L) significantly increases reactive oxygen species (ROS) generation and lipid peroxidation under ultraviolet B (UV-B) light exposure, upregulates alpha-esterase, hemoglobin, and vitellogenin mRNA, and significantly affects daphnid survival. [5]
Synonyms	2-Sulfanilamidothiazole

Chemical Properties

Molecular Weight	255.32
Formula	C₉H₉N₃O₂S₂
Cas No.	72-14-0
Smiles	Nc1ccc(cc1)S(=O)(=O)Nc1nccs1
Relative Density.	1.561g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (979.16 mM), Sonication is recommended.

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

In Vivo Formulation

10% DMSO+90% Saline: 10 mg/mL (39.17 mM), Solution.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9167 mL	19.5833 mL	39.1665 mL	195.8327 mL
5 mM	0.7833 mL	3.9167 mL	7.8333 mL	39.1665 mL
10 mM	0.3917 mL	1.9583 mL	3.9167 mL	19.5833 mL
20 mM	0.1958 mL	0.9792 mL	1.9583 mL	9.7916 mL
50 mM	0.0783 mL	0.3917 mL	0.7833 mL	3.9167 mL
100 mM	0.0392 mL	0.1958 mL	0.3917 mL	1.9583 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc