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Sterculic acid

Catalog No. T41253 CAS 738-87-4

Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].

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Sterculic acid, CAS 738-87-4

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25 mg	35 days	$ 990.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Sterculic acid, a stearoyl-CoA desaturase-1 (SCD1) inhibitor, effectively suppresses delta-9 desaturase (Δ9D) activity in a dose-dependent manner, exhibiting an inhibition concentration (IC50) value of 0.9 μM [1].
In vitro	Sterculic acid (SA), a cyclopropene fatty acid derived from Sterculia foetida seeds, exhibits diverse biological activities, including the reduction of adrenomedullin expression (AP, RP, APS, IML, in preparation) and mediating anti-inflammatory and protective effects. It also demonstrates a potent luteolytic effect in ovines by inhibiting progesterone synthesis, leading to luteal regression [2].
In vivo	Sterculic acid is suggested as a promising intervention for metabolic syndrome (MS), as it effectively inhibits the function of stearoyl-CoA desaturase-1 (SCD1) in vivo [3].

Molecular Weight	294.47
Formula	C19H34O2
CAS No.	738-87-4

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Powder: -20°C for 3 years | In solvent: -80°C for 1 year

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Sterculic acid 738-87-4 inhibitor inhibit

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