store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Seviteronel is an effective CYP17 lyase inhibitor (h-Lyase IC50=69 nM). In a hamster model of androgen biosynthesis inhibition, it demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 198.00 | |
5 mg | In stock | $ 347.00 | |
25 mg | 6-8 weeks | $ 1,140.00 | |
50 mg | 6-8 weeks | $ 1,490.00 | |
100 mg | 6-8 weeks | $ 1,990.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 382.00 |
Description | Seviteronel is an effective CYP17 lyase inhibitor (h-Lyase IC50=69 nM). In a hamster model of androgen biosynthesis inhibition, it demonstrated both exceptional in vitro lyase/hydroxylase selectivity (~10-fold) and oral activity. |
Targets&IC50 | CYP17 Lyase:69 nM |
Synonyms | VT-464 |
Molecular Weight | 399.34 |
Formula | C18H17F4N3O3 |
CAS No. | 1610537-15-9 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Seviteronel 1610537-15-9 Others VT-464 VT 464 VT464 inhibitor inhibit