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Sennidin B

Catalog No. TN1034 CAS 517-44-2

Sennidin B stimulates glucose incorporation in rat adipocytes.

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Sennidin B, CAS 517-44-2

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Sennidin B stimulates glucose incorporation in rat adipocytes.

In vitro

The bacterium hydrolyzed sennosides A and Sennidin B to sennidin A and Sennidin B via sennidin A and Sennidin B 8-monoglucosides, respectively. Among nine species of Bifidobacterium having beta-glucosidase activity, only Bifidobacterium dentium and B. adolescentis metabolized sennoside B to Sennidin B, suggesting that the sennoside-metabolizing bacteria produce a novel type of beta-glucosidase capable of hydrolyzing sennosides to sennidins[1]

Molecular Weight	538.47
Formula	C30H18O10
CAS No.	517-44-2

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Isolation of a human intestinal anaerobe, Bifidobacterium sp. strain SEN, capable of hydrolyzing sennosides to sennidins.Appl Environ Microbiol. 1994 Mar;60(3):1041-3.

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Keywords

Sennidin B 517-44-2 Cytoskeletal Signaling Metabolism Microbiology/Virology PI3K/Akt/mTOR signaling Proteases/Proteasome HCV Protease transporter Akt PI3K inhibit Protein kinase B Hepatitis C virus PKB HCV Inhibitor Glucose transporter GLUT inhibitor

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