store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular disease and hypertension, among other diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 700.00 | |
5 mg | In stock | $ 1,800.00 |
Description | SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular disease and hypertension, among other diseases. |
In vivo | In spontaneously hypertensive rats treated with SM-6586, the survival rate after bilateral common carotid artery ligation is higher, the brain water content is lower, and the ATP level is higher, while lactate level is decreased. In focal ischemia models, the SM-treated group shows a reduction of T1 relaxation time. Additionally, the brain water content is significantly decreased in the SM-treated group[1]. |
Molecular Weight | 489.52 |
Formula | C26H27N5O5 |
CAS No. | 103898-38-0 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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SM-6586 103898-38-0 Membrane transporter/Ion channel Na+/Ca2+ Exchanger Sodium Channel SM6586 SM 6586 inhibitor inhibit