Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 2,420.00 | |
50 mg | 10-14 weeks | $ 3,180.00 | |
100 mg | 10-14 weeks | $ 4,300.00 |
Description | Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively). |
Targets&IC50 | TPH1:33 nM, TPH2:7 nM, 5-HT: |
In vivo | Rodatristat (10-50 mg/kg; p.o.; mice) treatment reduces intestinal 5-HT concentrations at 50 mg/kg. Their efficacy drops off significantly at the lower 10 mg/kg dose [1]. |
Synonyms | KAR5417 |
Molecular Weight | 561.98 |
Formula | C27H27ClF3N5O3 |
CAS No. | 1673568-73-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Rodatristat 1673568-73-4 Others KAR5417 KAR-5417 KAR 5417 inhibitor inhibit