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Rafabegron

Catalog No. T34256 CAS 244081-42-3

Synonyms: TAK-677, TAK677, AD9677, AD-9677, TAK 677, AD 9677

Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Rafabegron, CAS 244081-42-3

Pack Size	Availability	Price/USD
1 mg	In stock	$ 290.00
5 mg	In stock	$ 713.00
10 mg	In stock	$ 987.00
25 mg	In stock	$ 1,480.00
50 mg	In stock	$ 1,980.00
100 mg	In stock	$ 2,730.00

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Purity: 100%

ee: 100%

Biological Description

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Description

Rafabegron (TAK677) is a potent and selective β3 adrenergic receptor agonist for the study of diabetes and obesity.

Synonyms	TAK-677, TAK677, AD9677, AD-9677, TAK 677, AD 9677
Molecular Weight	402.87
Formula	C21H23ClN2O4
CAS No.	244081-42-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Thiagamoorthy G, Giarenis I, Cardozo L. Early investigational β3 adreno-receptor agonists for the management of the overactive bladder syndrome. Expert Opin Investig Drugs. 2015;24(10):1299-306. doi: 10.1517/13543784.2015.1076390. Epub 2015 Aug 14. PubMed PMID: 26292923. 2. Kullmann FA, Downs TR, Artim DE, Limberg BJ, Shah M, Contract D, de Groat WC, Rosenbaum JS. Urothelial beta-3 adrenergic receptors in the rat bladder. Neurourol Urodyn. 2011 Jan;30(1):144-50. doi: 10.1002/nau.20965. PubMed PMID: 21046653; PubMed Central PMCID: PMC3395322. 3. Fujita M, Ueda T, Iwata M. Stabilization by meglumine of an amine compound degraded by formaldehyde in tablets. Int J Pharm. 2010 Feb 15;386(1-2):195-200. doi: 10.1016/j.ijpharm.2009.11.017. Epub 2009 Dec 2. PubMed PMID: 19931605. 4. Kullmann FA, Limberg BJ, Artim DE, Shah M, Downs TR, Contract D, Wos J, Rosenbaum JS, de Groat WC. Effects of beta3-adrenergic receptor activation on rat urinary bladder hyperactivity induced by ovariectomy. J Pharmacol Exp Ther. 2009 Sep;330(3):704-17. doi: 10.1124/jpet.109.155010. Epub 2009 Jun 10. PubMed PMID: 19515967; PubMed Central PMCID: PMC2729793.

Related compound libraries

This product is contained In the following compound libraries：

Membrane Protein-targeted Compound Library GPCR Compound Library Bioactive Compound Library Anti-Cancer Compound Library Bioactive Compounds Library Max

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Rafabegron 244081-42-3 GPCR/G Protein Neuroscience Adrenergic Receptor TAK-677 TAK677 AD9677 AD-9677 TAK 677 AD 9677 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.