Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 109.00 | |
5 mg | Inquiry | $ 525.00 |
Description | Prostaglandin D2 ethanolamide (PGD2-EA) is a bioactive lipid produced by the sequential metabolism of anandamide (arachidonoyl ethanolamide) by cyclooxygenase (COX) enzymes, in particular by COX-2, and PGD synthase. The biosynthesis of PGD2-EA from anandamide can also be increased when anandamide metabolism is diminished by deletion of fatty acid amide hydrolase. PGD2-EA is inactive against recombinant prostanoid receptors, including the D prostanoid receptor. It increases the frequency of miniature inhibitory postsynaptic currents in primary cultured hippocampal neurons, an effect which is the opposite of that induced by anandamide.. PGD2-EA also induces apoptosis in colorectal carcinoma cell lines. |
Synonyms | Prostaglandin D2 Ethanolamide |
Molecular Weight | 395.54 |
Formula | C22H37NO5 |
CAS No. | 398138-28-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8.3 mg/mL
DMF: 8.3 mg/mL
Ethanol: 12.5 mg/mL
PBS (pH 7.2): 2.5 mg/mL
You can also refer to dose conversion for different animals. More
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Prostaglandin D2 Ethanolamide 398138-28-8 Prostaglandin D-2 Ethanolamide inhibitor inhibit