Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes, has antibacterial, anticancer, antimalarial activities.
Pack Size | Availability | Price/USD | Quantity |
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25 mg | Inquiry | $ 1,520.00 |
Description | Polyketomycin is a tetracyclic quinone glycoside antibiotic isolated from Streptomyces sp. or Streptomyces diastatochromogenes, has antibacterial, anticancer, antimalarial activities. |
In vitro | Polyketomycin demonstrates inhibitory activity against a spectrum of cancers, including L1210 leukemia, EL-4 leukemia, P388 leukemia, Ehrlich carcinoma, IMC carcinoma, colon 26 adenocarcinoma, Meth A fibrosarcoma, FS-3 fibrosarcoma, and B16-BL10 melanoma, with respective IC50 values of 3.3 μg/mL, 2.1 μg/mL, 5.2 μg/mL, 1 μg/mL, 0.9 μg/mL, 1.8 μg/mL, 2.4 μg/mL, 1.5 μg/mL, and 1.6 μg/mL[1]. |
In vivo | In mice, Polyketomycin acute toxicity is estimated to be 6.25-12.5mg/kg[1]. |
Molecular Weight | 864.84 |
Formula | C44H48O18 |
CAS No. | 200625-47-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Polyketomycin 200625-47-4 Others inhibitor inhibit