Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 5 days | $ 332.00 |
Description | Podocarpusflavone A is a DNA topoisomerase I inhibitor. It has moderated anti-proliferative activity induce cell apoptosis in MCF-7. |
Targets&IC50 | Topoisomerase I:119.425 μM (IC50) |
In vitro | Podocarpusflavone A shows significant inhibitions against KB, DLD, HEp-2, MCF-7 tumor cell lines (ED50 4.56-16.24 μg/mL) and induces cell apoptosis in MCF-7 via mainly sub-G1/S phase arrest. PF (40 ug/mL, 24 hr) significantly induced about 10 folds of cell deaths and growth arrest in S-phase than the control group. |
Source |
Molecular Weight | 552.48 |
Formula | C31H20O10 |
CAS No. | 22136-74-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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Podocarpusflavone A 22136-74-9 DNA Damage/DNA Repair Topoisomerase inhibitor inhibit