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Phenyl-β-D-glucopyranoside

Catalog No. TN6747 CAS 1464-44-4

Synonyms: PHENYL-B-D-GLUCOPYRANOSIDE

Phenyl-β-D-glucopyranoside (PHENYL-B-D-GLUCOPYRANOSIDE) is a component of Phellodendron amurense with anti-cancer and anti-inflammatory activities.

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Phenyl-β-D-glucopyranoside Chemical Structure

Phenyl-β-D-glucopyranoside, CAS 1464-44-4

Pack Size	Availability	Price/USD	Quantity
200 mg	In stock	$ 29.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 99.94%

Purity: 97.21%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Phenyl-β-D-glucopyranoside (PHENYL-B-D-GLUCOPYRANOSIDE) is a component of Phellodendron amurense with anti-cancer and anti-inflammatory activities.

In vitro

Phenyl-β-D-Glucopyranoside Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells. Phenyl-β-D-glucopyranoside not only inhibited nitric oxide (NO) production but also significantly inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) without inducing cytotoxicity. Phenyl-β-D-glucopyranoside also attenuated proinflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and other inflammation-related genes, such as IL-6 in a concentration-dependent manner. Furthermore, phenyl-β-D-glucopyranoside abolished increased adhesion, ninjurin 1 (Ninj1) expression, and matrix metalloproteinase (MMP) activity induced by endotoxin treatment. Finally, phenyl-β-D-glucopyranoside inhibited the nuclear translocation of nuclear factor-κB (NF-κB), which is one of the most important transcription factors involved in the inflammatory process.

Synonyms	PHENYL-B-D-GLUCOPYRANOSIDE
Molecular Weight	256.25
Formula	C12H16O6
CAS No.	1464-44-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: soluble

DMSO: 60 mg/ml (234.15 mM)

References and Literature

1. Hwang SJ, Lee HJ. Phenyl-β-D-Glucopyranoside Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells. Inflammation. 2015;38(3):1071-9.

Related compound libraries

This product is contained In the following compound libraries：

Tobacco Monomer Library Anti-Cancer Active Compound Library Natural Product Library for HTS Selected Plant-Sourced Compound Library Bioactive Compounds Library Max Immunology/Inflammation Compound Library RO5 Drug-like Natural Product Library Anti-Tumor Natural Product Library Natural Product Library Bioactive Compound Library

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Keywords

Phenyl-β-D-glucopyranoside 1464-44-4 Others Phenyl-beta-D-glucopyranoside PhenylβDglucopyranoside Phenyl β D glucopyranoside PHENYL-B-D-GLUCOPYRANOSIDE inhibitor inhibit

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