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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6070 | (E/Z)-Rigosertib sodium | (E/Z) ON-01910 sodium | PLK |
ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidativ... |