Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nigericin is an antibiotic derived from Streptomyces hygroscopicus that acts as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin can be an NLRP3 activator that causes the release of IL-1β as a NALP3-dependent manner. Nigericin induces eryptosis, an effect paralleled by ROS formation, and in part due to the induction of oxidative stress. Nigericin causes apoptosis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | Inquiry | $ 1,520.00 |
Description | Nigericin is an antibiotic derived from Streptomyces hygroscopicus that acts as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin can be an NLRP3 activator that causes the release of IL-1β as a NALP3-dependent manner. Nigericin induces eryptosis, an effect paralleled by ROS formation, and in part due to the induction of oxidative stress. Nigericin causes apoptosis. |
Molecular Weight | 724.96 |
Formula | C40H68O11 |
CAS No. | 28380-24-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Nigericin 28380-24-7 Others inhibitor inhibit