Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 33.00 | |
100 mg | In stock | $ 46.00 | |
200 mg | In stock | $ 58.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Nadifloxacin (OPC7251) has been used in trials studying the treatment of Acne Vulgaris. |
In vitro | Nadifloxacin is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Nadifloxacin inhibits the enzyme DNA gyrase that is involved in bacterial DNA synthesis and replication, thus inhibiting the bacterial multiplication. In vitro studies of nadifloxacin show potent and broad-spectrum antibacterial activity against aerobic Gram-positive, Gram-negative and anaerobic bacteria. Additionally, studies also suggest that the effectiveness of nadifloxacin in inflammatory acne lesions may be attributed to its inhibitory effect on pro-inflammatory cytokines like interleukin (IL)-1α, IL-6, and IL-8 which also play an important role in acne pathogenesis. |
Synonyms | OPC7251 |
Molecular Weight | 360.38 |
Formula | C19H21FN2O4 |
CAS No. | 124858-35-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
DMSO: 16 mg/mL (44.4 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Nadifloxacin 124858-35-1 Microbiology/Virology Antibacterial Antibiotic OPC7251 Inhibitor Bacterial inhibit OPC 7251 OPC-7251 inhibitor