Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
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Description | N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | n-methyl-n-methyl-o-m-peg4-o-propargyl-peg4-cy5 |
Molecular Weight | 855.5 |
Formula | C47H67ClN2O10 |
CAS No. | 2107273-50-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 2107273-50-5 Others N-methyl-N'-methyl-O-(m-PEG-4)-O'-(propargyl-PEG4)-Cy5 N methyl N' methyl O (m PEG4) O' (propargyl PEG4) Cy5 n-methyl-n-methyl-o-m-peg4-o-propargyl-peg4-cy5 NmethylN'methylO(mPEG4)O'(propargylPEG4)Cy5 inhibitor inhibit