keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 50.00 | |
10 mg | In stock | $ 68.00 | |
25 mg | In stock | $ 118.00 | |
50 mg | In stock | $ 187.00 | |
100 mg | In stock | $ 281.00 | |
200 mg | In stock | $ 422.00 |
Description | N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM). |
In vitro | N-Formyl-Met-Leu-Phe receptor is associated with a Ni GTP regulatory protein, and N-Formyl-Met-Leu-Phe complex is important in the control of several neutrophil functions[1]. |
In vivo | N-Formyl-Met-Leu-Phe(fMLP) promoted bone formation in zebrafish and rabbits, suggesting its physiological relevance in vivo[2]. |
Animal Research | ebrafish (Danio rerio) embryos were collected from spontaneous spawnings reared at 28.5 ℃. Three days postfertilization (~1 day after hatching), feeding of the commercial powder for baby fish was started. Zebrafish embryos were stimulated with fMLP from 8 to 48 h postfertilization (hpf), washed, and raised at 28.5 ℃. At 5 days postfertilization (dpf), 20 zebrafish were stained with Alizarin Red for examination of the effect of fMLP on bone formation. Zebrafish were fixed in 4% paraformaldehyde for 12–18 h. Following fixation, fish were depigmented overnight in 1% KOH containing 3% H2O2 and immersed for 2 h in 0.5% KOH containing 0.05% Alizarin Red, pH 4.2. Alizarin-stained fish were then cleared again in 1% KOH and observed under a microscope[2]. |
Synonyms | fMLP, N-Formyl-MLF |
Molecular Weight | 437.55 |
Formula | C21H31N3O5S |
CAS No. | 59880-97-6 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 82.5 mg/mL (188.55 mM)
You can also refer to dose conversion for different animals. More
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N-Formyl-Met-Leu-Phe 59880-97-6 Apoptosis TNF TNF Receptor TNFR Inhibitor fMLP NFormylMetLeuPhe N-Formyl-MLF Tumor Necrosis Factor Receptor inhibit N Formyl Met Leu Phe inhibitor