Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Description | N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 807.76 |
Formula | C38H42F5N5O9 |
CAS No. | T18414 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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N-Fmoc-N'-(azido-PEG4)-L-Lysine-PFP ester T18414 Others N-Fmoc-N'-(azido-PEG-4)-L-Lysine-PFP ester N Fmoc N' (azido PEG4) L Lysine PFP ester NFmocN'(azidoPEG4)LLysinePFP ester inhibitor inhibit