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N-Desethyl amodiaquine

Name: N-Desethyl amodiaquine
Brand: TargetMol
SKU: T12154
Price: 105 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12154Cas No. 79352-78-6

N-Desethyl amodiaquine is an antiparasitic agent and the major bioactive amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.

N-Desethyl amodiaquine

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Purity: 99.58%

Catalog No. T12154Cas No. 79352-78-6

N-Desethyl amodiaquine is an antiparasitic agent and the major bioactive amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$105	-	In Stock
5 mg	$259	-	In Stock
10 mg	$478	-	In Stock
25 mg	$898	-	In Stock
1 mL x 10 mM (in DMSO)	$286	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.58%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

N-Desethyl amodiaquine is an antiparasitic agent and the major bioactive amodiaquine metabolite. Its IC50 values against strains V1/S and 3D7 were 97 nM and 25 nM, respectively.

Chemical Properties

Molecular Weight	327.81
Formula	C₁₈H₁₈ClN₃O
Cas No.	79352-78-6
Smiles	CCNCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O
Relative Density.	1.304 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (381.32 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (12.2 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0505 mL	15.2527 mL	30.5055 mL	152.5274 mL
5 mM	0.6101 mL	3.0505 mL	6.1011 mL	30.5055 mL
10 mM	0.3051 mL	1.5253 mL	3.0505 mL	15.2527 mL
20 mM	0.1525 mL	0.7626 mL	1.5253 mL	7.6264 mL
50 mM	0.0610 mL	0.3051 mL	0.6101 mL	3.0505 mL
100 mM	0.0305 mL	0.1525 mL	0.3051 mL	1.5253 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc