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Myomodulin acetate(110570-93-9 free base)

Catalog No. TP1852L CAS TP1852L

Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.

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Myomodulin acetate(110570-93-9 free base) Chemical Structure

Myomodulin acetate(110570-93-9 free base), CAS TP1852L

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1 mg	In stock	$ 59.00
5 mg	In stock	$ 171.00
10 mg	In stock	$ 263.00
25 mg	In stock	$ 475.00
50 mg	In stock	$ 695.00
100 mg	In stock	$ 988.00
500 mg	In stock	$ 1,980.00

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Purity: 99.24%

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Description

Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.

In vitro

Myomodulin decreases period and increases spike frequency in oscillator heart interneurons. Myomodulin enhances the hyperpolarization-activated cation current and inhibits the electrogenic Na/K pump[1]. A myomodulin peptide has been suggested to mediate the response of the giant glial cells to stimulation of the Leydig interneuron in the central nervous system of the leech Hirudo medicinalis. The peptide evokes a membrane outward current (EC50 approximately 2 μM), which neither desensitizes nor shows any sign of run-down, and elicits a K+ conductance increase of the glial cell membrane[3]. Myomodulin modulate ion channels in a wide variety of organisms including Aplysia, Lymnaea, and Pleurobranchaea. Myomodulin differentially modulates the potassium currents and reduces the amplitude of the Ca2+ current by 20%[2].

Molecular Weight	906.17
Formula	C38H71N11O10S2
CAS No.	TP1852L

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Tobin AE, et al. Myomodulin increases Ih and inhibits the NA/K pump to modulate bursting in leech heart interneurons. J Neurophysiol. 2005 Dec;94(6):3938-50. 2. Wang Y, et al. Modulatory effects of myomodulin on the excitability and membrane currents in Retzius cells of the leech. J Neurophysiol. 1999 Jul;82(1):216-25. 3. Britz FC, et al. Membrane responses of the leech giant glial cell to the peptide transmitter myomodulin. Peptides. 2002 Dec;23(12):2117-25.

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Potassium Channel Blocker Library Anti-Hypertension Compound Library Sodium Channel Blocker Library Ion Channel Inhibitor Library Calcium Channel Compound Library Metabolism Compound Library NO PAINS Compound Library

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Keywords

Myomodulin acetate(110570-93-9 free base) TP1852L Membrane transporter/Ion channel Metabolism Calcium Channel Potassium Channel Sodium Channel Myomodulin acetate(110570 93 9 free base) Myomodulin acetate(110570939 free base) inhibitor inhibit

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