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Morellic acid

Catalog No. TN1112 CAS 5304-71-2

Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity.

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Morellic acid, CAS 5304-71-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 89.00
5 mg	In stock	$ 193.00
10 mg	In stock	$ 328.00
25 mg	In stock	$ 553.00
50 mg	In stock	$ 789.00
1 mL * 10 mM (in DMSO)	In stock	$ 256.00

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Purity: 99.43%

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Description	Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity.
In vitro	An improved HPLC method was developed to simultaneously quantify 12 caged xanthones, including three pairs of epimers and four pairs of trans-cis isomers, i.e. forbesione, isoMorellic acid, Morellic acid, R-30-hydroxygambogic acid, S-30-hydroxygambogic acid, isogambogenic acid, gambogenic acid, gambogellic acid, R-isogambogic acid, S-isogambogic acid, R-gambogic acid and S-gambogic acid. This method was validated to be sensitive, precise and accurate with limits of detection of 0.03-0.08 microg/mL, overall intra-day and inter-day variations less than 7.9% and overall recovery over 93.2%. The correlation coefficients (r(2)) of the calibration curves were higher than 0.995 for all analytes. The newly established method was successfully applied to reveal the difference in the chemical profiles and contents of these analytes in gamboges from different origins.
Source	Natural Products > Clusiaceae > Garcinia

Molecular Weight	560.63
Formula	C33H36O8
CAS No.	5304-71-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 50 mg/mL (89.19 mM)

References and Literature

1. Improved high-performance liquid chromatographic method for simultaneous determination of 12 cytotoxic caged xanthones in gamboges, a potential anticancer resin fromGarcinia hanburyi.Biomedical Chromatography, 2008, 22(6):637-644.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Anti-Tumor Natural Product Library NO PAINS Compound Library Covalent Inhibitor Library Selected Plant-Sourced Compound Library Bioactive Compounds Library Max Bioactive Compound Library Anti-Cancer Compound Library Natural Product Library Covalent Natural Product Library

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Keywords

Morellic acid 5304-71-2 Others cell antiangiogenic inhibit Inhibitor HUVEC inhibitor

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