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Morellic acid

Morellic acid
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Purity:99.43%
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Morellic acid

Catalog No. TN1112Cas No. 5304-71-2
Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity.
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Pack SizePriceAvailabilityQuantity
1 mg$89In Stock
5 mg$193In Stock
10 mg$328In Stock
25 mg$553In Stock
50 mg$789In Stock
1 mL x 10 mM (in DMSO)$256In Stock
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Product Introduction

Bioactivity
Description
Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity.
In vitro
An improved HPLC method was developed to simultaneously quantify 12 caged xanthones, including three pairs of epimers and four pairs of trans-cis isomers, i.e. forbesione, isoMorellic acid, Morellic acid, R-30-hydroxygambogic acid, S-30-hydroxygambogic acid, isogambogenic acid, gambogenic acid, gambogellic acid, R-isogambogic acid, S-isogambogic acid, R-gambogic acid and S-gambogic acid. This method was validated to be sensitive, precise and accurate with limits of detection of 0.03-0.08 microg/mL, overall intra-day and inter-day variations less than 7.9% and overall recovery over 93.2%. The correlation coefficients (r(2)) of the calibration curves were higher than 0.995 for all analytes. The newly established method was successfully applied to reveal the difference in the chemical profiles and contents of these analytes in gamboges from different origins.
Chemical Properties
Molecular Weight560.63
FormulaC33H36O8
Cas No.5304-71-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 50 mg/mL (89.19 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7837 mL8.9185 mL17.8371 mL89.1854 mL
5 mM0.3567 mL1.7837 mL3.5674 mL17.8371 mL
10 mM0.1784 mL0.8919 mL1.7837 mL8.9185 mL
20 mM0.0892 mL0.4459 mL0.8919 mL4.4593 mL
50 mM0.0357 mL0.1784 mL0.3567 mL1.7837 mL

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