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Malvidin-3-galactoside chloride

Catalog No. TN1908   CAS 30113-37-2
Synonyms: Malvidin-3-O-galactoside chloride

Malvidin-3-O-galactoside chloride has antioxidant activity.

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Malvidin-3-galactoside chloride Chemical Structure
Malvidin-3-galactoside chloride, CAS 30113-37-2
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Malvidin-3-O-galactoside chloride has antioxidant activity.
In vitro The hepato-cellular accumulation of widely used drugs such as statins and some anticancer drugs is mediated by the liver-specific OATP1B1 and OATP1B3, thus any interference with expression of these particular transporters might influence therapeutic outcomes. We evaluated the effects of 21 anthocyanins and their corresponding 6 anthocyanidins on the expression levels of SLCO1B1/SLCO1B3 by RT-qPCR. Changes in OATP protein levels were confirmed by western blotting. Our data show that OATP1B1 responds differently to anthocyans compared with OATP1B3. We observed the induction of SLCO1B1 gene and OATP1B1 protein in four hepatocyte samples by the anthocyanins malvin chloride, Malvidin-3-O-galactoside chloride and cyanidin-3-O-sophoroside chloride. For SLCO1B3, a reduction in the expression levels was seen with delphin chloride and the anthocyanidin pelargonidin. Although the values varied considerably between primary hepatocyte isolates from different individuals, a mean induction of SLCO1B1 (up to 60%) and reduction of SLCO1B3 (by less than 25%) were detected.
Source
Synonyms Malvidin-3-O-galactoside chloride
Molecular Weight 528.89
Formula C23H25ClO12
CAS No. 30113-37-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.Food Funct. 2015 Mar 11;6(3):772-9.

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Keywords

Malvidin-3-galactoside chloride 30113-37-2 Others Malvidin-3-O-galactoside Chloride Malvidin3galactoside chloride Malvidin-3-O-galactoside chloride Malvidin-3-galactoside Chloride Malvidin 3 galactoside chloride inhibitor inhibit

 

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