Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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500 mg | 5 days | Inquiry |
Description | Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 254.16 |
Formula | C8H9F3N2O4 |
CAS No. | 146474-00-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Mal-NH2 TFA 146474-00-2 Others Mal NH2 TFA MalNH2 TFA Mal-NH-2 TFA inhibitor inhibit