Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | 5 days | $ 446.00 |
Description | MK-0429 is an orally active, selective, and nonpeptide antagonist of αvβ3 integrin (IC50: 80 nM). |
Targets&IC50 | αvβ3 integrin:80 nM |
In vivo | MK-0429 is safe and efficacious in obviously reducing melanoma metastasis in the lungs. MK-0429 (100 or 300 mg/kg, p.o., twice daily b.i.d., 2 weeks) decreases metastatic tumor colony formation and area in the lungs [1]. |
Synonyms | L-000845704 |
Molecular Weight | 439.51 |
Formula | C23H29N5O4 |
CAS No. | 227963-15-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (568.82 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MK-0429 227963-15-7 Others MK 0429 L 000845704 MK0429 L000845704 L-000845704 inhibitor inhibit