Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Licoricesaponin A3 shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 < 100 μMol/L.
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5 mg | Inquiry | $ 2,198.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | Inquiry |
Description | Licoricesaponin A3 shows the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μMol/L. |
In vitro | The compounds were separated and purified by solvent and chromatographic methods. Their structures were identified by spectroscopic techniques. Fourteen triterpenoid saponins isolated from 50% ethanol extract of the roots and rhizomes of G. uralensis were identified as uralsaponin C (1), uralsaponin D (2), Licoricesaponin A3 (3), uralsaponin F (4), 22β-acetoxyl-glycyrrizin (5), 24-hydroxyl-licorice-saponin E2 (6), licorice-saponin E2 (7), licorice-saponin G2 (8), 22β-acetoxyl-glyrrhaldehyde (9), 3β-O-[β-D-glucuronopyranosyl-(1??2) - β-D-glucuronopyranosyl]-glycyrretol (10), araboglycyrrhizin (11), licorice-saponin J2 (12), glycyrrhizin (13), and glycyrrhetic acid monoglucuronide (14). Compounds 1-14 showed the cytotoxic activity against the human cancer cell lines MGC-803, SW620, and SMMC-7721 with IC50 > 100 μmol/L. The aglycones of compounds 2, 6-8, and 13 displayed the inhibition on the growth of cancer cells with IC50 at 18.3-41.6 μmol/L[1] |
Source |
Molecular Weight | 985.083 |
Formula | C48H72O21 |
CAS No. | 118325-22-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Licoricesaponin A3 118325-22-7 Others Licoricesaponin A-3 inhibitor inhibit