Powder: -20°C for 3 years
In solvent: -80°C for 2 years
EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective.
Description | EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively). Neuroprotective. |
Targets&IC50 | EphA4:0.8 μM(Kd) |
Molecular Weight | 1525.78 |
Formula | C76H112N14O19 |
CAS No. | TP1895L1 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 10 mM
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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KYL acetate(676657-00-4 free base) TP1895L1 蛋白酪氨酸激酶 Ephrin Receptor KYL acetate(676657 00 4 free base) KYL acetate(676657004 free base) Inhibitor inhibitor inhibit