Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MRP1.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 37.00 | |
2 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 79.00 | |
10 mg | In stock | $ 133.00 | |
25 mg | In stock | $ 293.00 | |
50 mg | In stock | $ 536.00 | |
100 mg | In stock | $ 773.00 | |
500 mg | In stock | $ 1,590.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | KS176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter, showing no inhibitory activity against P-gp or MRP1. |
Targets&IC50 | BCRP(Pheo A):0.59 μM |
Kinase Assay | Phospholipase D activity is quantified using our established method of measuring the formation of [32P]-radiolabeled PBt. Cellular lipids are extracted and PBt is isolated using our published methods of lipid extraction and thin layer chromatographic separation, respectively. Radioactivity is measured using liquid scintillation counting and quantified as DPM normalized to 106 counts in the total cellular lipid extract or as percentage of control (vehicle-treated cells). |
Molecular Weight | 405.4 |
Formula | C22H19N3O5 |
CAS No. | 1253452-78-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 35 mg/mL
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
KS176 1253452-78-6 Membrane transporter/Ion channel BCRP Potassium Channel ABCG2 Inhibitor inhibit KS 176 Breast cancer resistance protein KS-176 inhibitor