Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 64.00 | |
10 mg | In stock | $ 80.00 | |
25 mg | In stock | $ 123.00 | |
50 mg | In stock | $ 163.00 | |
100 mg | In stock | $ 247.00 | |
200 mg | In stock | $ 372.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 70.00 |
Description | JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2) |
Targets&IC50 | BRD4(2):33 nM, BRD4(1):77 nM |
In vitro | JQ-1 carboxylic acid is an inhibitor of bromodomain and extra terminal domain (BET) family proteins, blocking their interaction with acetylated histones[1],it has been used as a chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis[2][3]. |
Synonyms | JQ-1 carboxylic acid |
Molecular Weight | 400.88 |
Formula | C19H17ClN4O2S |
CAS No. | 202592-23-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 155 mg/mL (386.65 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
JQ-1 (carboxylic acid) 202592-23-2 Chromatin/Epigenetic Epigenetic Reader Domain carboxylic acid JQ 1 (carboxylic acid) JQ 1 JQ-1 Inhibitor JQ1 (carboxylic acid) polypeptide JQ-1 carboxylic acid JQ1 chromatin bromodomain inhibit remodeling inhibitor