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Imirestat

Catalog No. T15568 CAS 89391-50-4

Synonyms: 咪瑞司他, Alcon 1576, AL 1576, HOE 843

Imirestat is an aldose reductase inhibitor that can be used in diabetes research.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Imirestat, CAS 89391-50-4

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Imirestat is an aldose reductase inhibitor that can be used in diabetes research.
In vivo	Administration of 1 mg/kg Imirestat increased nerve conduction velocity, however, had no effect on resistance to hypoxic conduction block or deficits in insulin-stimulated Uban-sensitive ATPase activity[1].

Synonyms	咪瑞司他, Alcon 1576, AL 1576, HOE 843
Molecular Weight	286.23
Formula	C15H8F2N2O2
CAS No.	89391-50-4

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 100 mg/mL (349.37 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Carrington AL, et al. Aldose reductase inhibition with imirestat-effects on impulse conduction and insulin-stimulation of Na+/K(+)-adenosine triphosphatase activity in sciatic nerves of streptozotocin-diabetic rats. Diabetologia. 1991 Jun;34(6):397-401.

Related Products

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Danshenol A 8-Lavandulylkaempferol Vicenin-1 Ganoderic acid C2 2'-acetylacteoside Zopolrestat Alpha-Estradiol Sulindac sulfone

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Imirestat 89391-50-4 代谢内分泌与激素 Reductase AL1576 HOE-843 inhibit Alcon 1576 AL-1576 HOE843 Aldose Reductase Alcon-1576 Inhibitor Alcon1576 AL 1576 HOE 843 inhibitor

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