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GS87

Catalog No. T8605 CAS 919936-70-2

Synonyms: 4-[5-[[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]thio]-1,3,4-oxadiazol-2-yl]pyridine

GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

GS87, CAS 919936-70-2

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
2 mg	In stock	$ 198.00
5 mg	In stock	$ 297.00
10 mg	In stock	$ 453.00
25 mg	In stock	$ 747.00
50 mg	In stock	$ 1,050.00
100 mg	In stock	$ 1,420.00
1 mL * 10 mM (in DMSO)	In stock	$ 313.00

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Purity: 99.47%

Biological Description

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Description	GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.
In vitro	GS87 potently inhibits growth of AML cells in mice with little effect on normal bone marrow cells. GS87 causes terminal differentiation of AML cells

Synonyms	4-[5-[[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]thio]-1,3,4-oxadiazol-2-yl]pyridine
Molecular Weight	337.36
Formula	C16H11N5O2S
CAS No.	919936-70-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMSO: 25 mg/mL (74.1 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Sophia, Hu, Masumi, et al. A Novel Glycogen Synthase Kinase-3 Inhibitor Optimized for Acute Myeloid Leukemia Differentiation Activity.[J]. Molecular Cancer Therapeutics, 2016.

Related compound libraries

This product is contained In the following compound libraries：

Stem Cell Differentiation Compound Library Inhibitor Library Antioxidant Compound Library Anti-Obesity Compound Library Antidepressant Compound Library Anti-Prostate Cancer Compound Library Anti-Pancreatic Cancer Compound Library Bioactive Compounds Library Max NO PAINS Compound Library Anti-Ovarian Cancer Compound Library

Related Products

Related compounds with same targets

3F8 GSK-3β inhibitor 8 ARN25068 CDK8-IN-12 EHT 1610 Aloisine B GSK-3 inhibitor 1 Lecanoric acid

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

GS87 919936-70-2 PI3K/Akt/mTOR signaling Stem Cells GSK-3 GS-87 GSK3α Inhibitor 4-[5-[[(3-Phenyl-1,2,4-oxadiazol-5-yl)methyl]thio]-1,3,4-oxadiazol-2-yl]pyridine Glycogen synthase kinase 3 MAPK GS 87 inhibit Glycogen synthase kinase-3 GSK3 AML differentiation GSK3β inhibitor

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