Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 56.00 | |
2 mg | In stock | $ 77.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 178.00 | |
25 mg | In stock | $ 297.00 | |
50 mg | In stock | $ 453.00 | |
100 mg | In stock | $ 655.00 | |
500 mg | In stock | $ 1,360.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 143.00 |
Description | GBR 12783 dihydrochloride (GBR12783 2HCl) is a specific, potent and selective dopamine uptake inhibitor. GBR 12783 dihydrochloride inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats. |
In vivo | GBR 12783 (10 mg/kg; intraperitoneal injection; for 100 minutes; male Sprague-Dawley rats) treatment reinforces specifically dopamine transmission only at synapses instantaneously active, increases hippocampal ACh release and improves memory performance in a passive avoidance task[1]. |
Synonyms | GBR12783 2HCl |
Molecular Weight | 485.49 |
Formula | C28H34Cl2N2O |
CAS No. | 67469-75-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (92.69 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
GBR 12783 dihydrochloride 67469-75-4 Others GBR 12783 GBR12783 2HCl GBR 12783 Dihydrochloride GBR12783 Dihydrochloride GBR-12783 GBR12783 GBR-12783 Dihydrochloride inhibitor inhibit