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Docosahexaenoic Acid methyl ester

Catalog No. T19294 CAS 2566-90-7

Synonyms: Methyl docosahexaenoate, all cis-DHA methyl ester

Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed.

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Docosahexaenoic Acid methyl ester Chemical Structure

Docosahexaenoic Acid methyl ester, CAS 2566-90-7

Pack Size	Availability	Price/USD	Quantity
100 mg	In stock	$ 50.00
1 mL * 10 mM (in DMSO)	In stock	$ 33.00

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Purity: 98.27%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Docosahexaenoic Acid methyl ester (all cis-DHA methyl ester) is a methylated docosahexaenoic acid analog that can be inserted into membrane phospholipids without being oxidized or hydrolyzed.

In vitro

After the application of methyl docosahexaenoate (DHA-Me), the incidence of sharp waves (SPW) relative to baseline appeared to decrease. In the absence of methyl docosahexaenoate (DHA), when bovine serum albumin (BSA) is exposed to a mixed functional oxidation system of Fe2+ and ascorbic acid (AsA), no new protein bands are produced. However, when BSA was incubated with DHA for only 24 hours, high molecular weight protein bands were observed. The incubation of BSA with 1.0 mM DHA resulted in a substantial increase in protein carbonyl content, while the addition of oxygen free radical scavenger resulted in a significant decrease in protein carbonyl content.

Synonyms	Methyl docosahexaenoate, all cis-DHA methyl ester
Molecular Weight	342.51
Formula	C23H34O2
CAS No.	2566-90-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

Ethanol: 100 mg/mL (291.96 mM), Sonication is recommended.

DMSO: 25 mg/mL (72.99 mM), Sonication is recommended.

References and Literature

1. Taha AY, et al. Selective reduction of excitatory hippocampal sharp waves by docosahexaenoic acid and its methyl ester analog ex-vivo. Brain Res. 2013 Nov 6;1537:9-17. 2. Liu W, et al. Formation of high-molecular-weight protein adducts by methyl docosahexaenoate peroxidation products. Biochim Biophys Acta. 2007 Feb;1774(2):258-66.

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Keywords

Docosahexaenoic Acid methyl ester 2566-90-7 Others inhibit Inhibitor Methyl docosahexaenoate all cis-DHA methyl ester inhibitor

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