Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dioxoisoindolin-O-PEG-OH (MW 2000) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROTACs (proteolysis targeting chimeras)[1].
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Description | Dioxoisoindolin-O-PEG-OH (MW 2000) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of PROTACs (proteolysis targeting chimeras)[1]. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Synonyms | (1,3-dioxoisoindolin-2-yl)-O-PEG-OH (MW 2000) |
Molecular Weight | N/A |
CAS No. | T17830 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Dioxoisoindolin-O-PEG-OH (MW 2000) T17830 Others (1,3-dioxoisoindolin-2-yl)-O-PEG-OH (1,3-dioxoisoindolin-2-yl)-O-PEG-OH (MW 2000) Dioxoisoindolin-O-PEG-OH DioxoisoindolinOPEGOH (MW 2000) Dioxoisoindolin O PEG OH (MW 2000) inhibitor inhibit