Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, DL-Glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. DL-Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. DL-Glyceraldehyde modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). DL-Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | In stock | $ 47.00 | |
25 mg | In stock | $ 76.00 | |
50 mg | In stock | $ 112.00 | |
100 mg | In stock | $ 165.00 | |
200 mg | In stock | $ 245.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 39.00 |
Description | DL-Glyceraldehyde (Glyceric aldehyde) is produced from the action of the enzyme glyceraldehyde dehydrogenase, which converts glycerol to glyceraldehyde using NADP as a cofactor. When present at sufficiently high levels, DL-Glyceraldehyde can be a cytotoxin and a mutagen. A cytotoxin is a compound that kills cells. A mutagen is a compound that causes mutations in DNA. DL-Glyceraldehyde is a highly reactive compound that can modify and cross-link proteins. DL-Glyceraldehyde modified proteins appear to be cytotoxic, depress intracellular glutathione levels, and induce reactive oxygen species (ROS) production (PMID: 14981296 ). DL-Glyceraldehyde has been shown to cause chromosome damage to human cells in culture and is mutagenic in the Ames bacterial test. |
Targets&IC50 | Aldose reductase:10 nM(Human) |
Synonyms | Glyceric aldehyde |
Molecular Weight | 90.08 |
Formula | C3H6O3 |
CAS No. | 56-82-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.4 mg/mL (48.85 mM)
You can also refer to dose conversion for different animals. More
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DL-Glyceraldehyde 56-82-6 Endocrinology/Hormones Metabolism Reductase DLGlyceraldehyde Glyceric aldehyde DL Glyceraldehyde inhibitor inhibit