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Coenzyme Q10
(Synonyms: Ubiquinone-10, CoQ10) Copy Product Info
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Synonyms: Ubiquinone-10, CoQ10
Catalog No. T2796 Copy Product Info
Purity: 99.88%
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Coenzyme Q10 (CoQ10) is a naturally occurring lipid-soluble quinone compound derived from Fusarium oxysporum. Coenzyme Q10 functions as an electron carrier in the mitochondrial respiratory chain, sustaining mitochondrial energy metabolism. Coenzyme Q10 is applicable in research on mitochondrial dysfunction, oxidative stress damage, cardiovascular diseases, and neurodegenerative disorders.
Cas No. 303-98-0
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 200 mg | $42 | In Stock | In Stock | |
| 500 mg | $91 | - | In Stock | |
| 1 g | $136 | - | In Stock | |
| 5 g | $197 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.88%
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Coenzyme Q10 (CoQ10) is a naturally occurring lipid-soluble quinone compound derived from Fusarium oxysporum. Coenzyme Q10 functions as an electron carrier in the mitochondrial respiratory chain, sustaining mitochondrial energy metabolism. Coenzyme Q10 is applicable in research on mitochondrial dysfunction, oxidative stress damage, cardiovascular diseases, and neurodegenerative disorders. |
| In vitro | Methods: Isolated rat liver mitochondria were treated with Coenzyme Q10 (16, 32, 48, 64, 80 μg/mL), and inorganic phosphate release was measured to reflect ATPase activity. Results: PCK and Coenzyme Q10 at all concentrations increased mitochondrial ATPase activity. [1] Methods: Primary mouse peritoneal macrophages were pretreated with Coenzyme Q10 (20 µM) for 2 hours, then stimulated with LPS (1 µg/mL) for 6, 12, or 18 hours. Reactive oxygen species (ROS) were detected using the DCFH-DA fluorescent probe. Results: Coenzyme Q10 treatment significantly inhibited LPS-induced ROS production in macrophages. [2] |
| In vivo | Methods: Coenzyme Q10 (600 mg/kg/day) was administered via oral gavage starting 3 days prior to myocardial infarction in mice, once daily, continuing until 28 days post-surgery. Results: Coenzyme Q10 significantly reduced the area of myocardial fibrosis following myocardial infarction and alleviated myocardial cell hypertrophy in the infarct margin zone. [2] |
| Synonyms | Ubiquinone-10, CoQ10 |
| Molecular Weight | 863.34 |
| Formula | C59H90O4 |
| Cas No. | 303-98-0 |
| Smiles | C(/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C)\C)\C)\C)\C)\C)\C)C=1C(=O)C(OC)=C(OC)C(=O)C1C |
| Relative Density. | 0.9145 g/cm3 (Estimated) |
| Storage | Store at low temperature,The compound is unstable in solution. Please use soon Powder: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature. | ||||||||||
| Solubility Information | DMF: 1 mg/mL (1.16 mM), Sonication and heating are recommended.  DMSO: < 1 mg/mL (insoluble or slightly soluble), The compound is unstable in solution, please use soon. | ||||||||||
Solution Preparation Table | |||||||||||
DMF
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | |||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Keywords
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Related Tags: Coenzyme Q10 chemical structure | Coenzyme Q10 in vivo | Coenzyme Q10 in vitro | Coenzyme Q10 formula | Coenzyme Q10 molecular weight
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