Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Cirsiliol is a selective inhibitor of 5-lipoxygenase and a competitive low-affinity ligand of benzodiazepine receptors.
Description | Cirsiliol is a selective inhibitor of 5-lipoxygenase and a competitive low-affinity ligand of benzodiazepine receptors. |
In vitro | Cirsiliol (0.01 to 300 μM) causes concentration-dependent relaxation of rat isolated ileum. Cirsiliol may inhibit Ca2+ influx but stimulates Ca2+ release from intracellular stores [1]. Treatment with Cirsiliol reduces the proliferation of NSCLC cells through the suppression of radiation-induced Notch-1 expression [2]. |
In vivo | In the xenograft mouse model, tumor volume is significantly reduced by combinational treatment with irradiation and rhamnetin or cirsiliol compared with irradiation alone [2]. |
Molecular Weight | 330.292 |
Formula | C17H14O7 |
CAS No. | 34334-69-5 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Cirsiliol 34334-69-5 代谢 Lipoxygenase Inhibitor inhibitor inhibit