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Catalog No. T15014   CAS 586976-24-1

CTPB is a p300 <a href="/target/Histone_Acetyltransferase" style="display: inline; color: #c13a36">Histone Acetyltransferase</a> (HAT) enzyme activator.

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CTPB, CAS 586976-24-1
Pack Size Availability Price/USD Quantity
5 mg 8-10 weeks $ 1,070.00
50 mg 8-10 weeks $ 2,180.00
100 mg 8-10 weeks $ 2,800.00
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Purity: 98%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description CTPB is a p300 histone acetyltransferase (HAT) enzyme activator.
In vitro CTPB is a synthetic activator of HAT. It promotes the transcription by increasing the H3 and H4 acetylation in the nucleosome.
Molecular Weight 554.13
Formula C31H43ClF3NO2
CAS No. 586976-24-1


Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Sivanandam M, et al. Investigation of activation mechanism and conformational stability of N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxybenzamide and N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamidein the active site of p300 histone acetyl transferase enzyme by molecular dynamics and binding free-energy studies. J Biomol Struct Dyn. 2018 Oct 9:1-38.

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An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
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Enter 10 into the Volume box and select the correct unit (milliliter)
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The answer of 19.713 mg appears in the Mass box


Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

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An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box


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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.


Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.


CTPB 586976-24-1 Chromatin/Epigenetic Epigenetic Reader Domain Inhibitor inhibitor inhibit