Home Tools
Log in
Cart

CID 2011756

Catalog No. T1863   CAS 638156-11-3
Synonyms: CID2011756, CID-2011756

CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CID 2011756 Chemical Structure
CID 2011756, CAS 638156-11-3
Pack Size Availability Price/USD Quantity
5 mg In stock $ 39.00
10 mg In stock $ 72.00
25 mg In stock $ 137.00
50 mg In stock $ 247.00
100 mg In stock $ 342.00
500 mg In stock $ 827.00
1 mL * 10 mM (in DMSO) In stock $ 43.00
Bulk Inquiry
Get quote
Select Batch  
Purity: 100%
Purity: 99.68%
Purity: 98.15%
Purity: 98%
Contact us for more batch information
Biological Description
Chemical Properties
Storage & Solubility Information
Description CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.
Targets&IC50 PKD1:3.2 μM, PKD2:0.6 μM, PKD3:0.7 μM
Kinase Assay Ub-PLA2 assay: Recombinant enzymes in 20 mM Tris-HCl, pH 8.0, 2 mM CaCl2 and 2 mM β-mercaptoethanol (DUB assay buffer) are preincubated with single doses or dose ranges of PR-619 or P22077 for 30 minutes in a 96 well plate before the addition of Ub-PLA2 and NBD C6-HPC. The liberation of a fluorescent product within the linear range of the assay is monitored at room temperature using a fluorescence plate reader. Vehicle (2%(v/v) DMSO) and 10 mM N-ethylmaleimide are included as controls. Where ≥60% inhibition is observed, EC50 values are determined using a sigmoidal dose response equation.
Synonyms CID2011756, CID-2011756
Molecular Weight 396.87
Formula C22H21ClN2O3
CAS No. 638156-11-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 19.8 mg/mL(50 mM)

TargetMolReferences and Literature

1. Sharlow ER, et al. PLoS One. 2011;6(10):e25134.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Active Compound Library Kinase Inhibitor Library NO PAINS Compound Library Bioactive Compound Library Apoptosis Compound Library Anti-Cancer Compound Library Metabolism Compound Library Cell Cycle Compound Library Bioactive Compounds Library Max Inhibitor Library

Related Products

Related compounds with same targets
SRPKIN-1 CRT0066101 Benzamidine hydrochloride GAK inhibitor 49 CRT0066101 dihydrochloride SBC-115337 Wortmannin CID755673

TargetMolDose Conversion

You can also refer to dose conversion for different animals. More

TargetMol In vivo Formulation Calculator (Clear solution)

Step One: Enter information below
Dosage
mg/kg
Average weight of animals
g
Dosing volume per animal
ul
Number of animals
Step Two: Enter the in vivo formulation
% DMSO
%
% Tween 80
% ddH2O
Calculate Reset

TargetMolCalculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculation
Molecular Weight Calculator
=
X
X

Molarity Calculator allows you to calculate the

  • Mass of a compound required to prepare a solution of known volume and concentration
  • Volume of solution required to dissolve a compound of known mass to a desired concentration
  • Concentration of a solution resulting from a known mass of compound in a specific volume
See Example

An example of a molarity calculation using the molarity calculator
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
Enter 197.13 into the Molecular Weight (MW) box
Enter 10 into the Concentration box and select the correct unit (millimolar)
Enter 10 into the Volume box and select the correct unit (milliliter)
Press calculate
The answer of 19.713 mg appears in the Mass box

X
=
X

Calculator the dilution required to prepare a stock solution

Calculate the dilution required to prepare a stock solution
The dilution calculator is a useful tool which allows you to calculate how to dilute a stock solution of known concentration. Enter C1, C2 & V2 to calculate V1.

See Example

An example of a dilution calculation using the Tocris dilution calculator
What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
Enter 10 into the Concentration (start) box and select the correct unit (millimolar)
Enter 50 into the Concentration (final) box and select the correct unit (micromolar)
Enter 20 into the Volume (final) box and select the correct unit (milliliter)
Press calculate
The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

=
/

Calculate the volume of solvent required to reconstitute your vial.

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial.
Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

g/mol

Enter the chemical formula of a compound to calculate its molar mass and elemental composition

Tip: Chemical formula is case sensitive: C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed n the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

bottom

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

CID 2011756 638156-11-3 Cell Cycle/Checkpoint Metabolism Serine/threonin kinase inhibit CID2011756 CID-2011756 Protein kinase D Inhibitor PKD inhibitor

 

TargetMol