Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bromo-PEG5-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker for PROTAC synthesis[1]. It is utilized in the construction of PROteolysis TArgeting Chimeras (PROTACs), which are heterobifunctional molecules designed to induce protein degradation.
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Description | Bromo-PEG5-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker for PROTAC synthesis[1]. It is utilized in the construction of PROteolysis TArgeting Chimeras (PROTACs), which are heterobifunctional molecules designed to induce protein degradation. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 465.31 |
Formula | C16H34BrO8P |
CAS No. | 1446282-41-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Bromo-PEG5-phosphonic acid diethyl ester 1446282-41-2 Others BromoPEG5phosphonic acid diethyl ester Bromo PEG5 phosphonic acid diethyl ester Bromo-PEG-5-phosphonic acid diethyl ester inhibitor inhibit