Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bis-PEG8-acid, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs and antibody-drug conjugates (ADCs)[1]. It serves as a cleavable ADC linker, facilitating the development of specialized compounds.
Pack Size | Availability | Price/USD | Quantity |
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100 mg | 5 days | Inquiry | |
500 mg | 5 days | Inquiry |
Description | Bis-PEG8-acid, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs and antibody-drug conjugates (ADCs)[1]. It serves as a cleavable ADC linker, facilitating the development of specialized compounds. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Molecular Weight | 470.51 |
Formula | C20H38O12 |
CAS No. | 1246189-43-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Bis-PEG8-acid 1246189-43-4 Others Bis PEG8 acid BisPEG8acid Bis-PEG-8-acid inhibitor inhibit