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Bidisomide

Catalog No. T12858 CAS 116078-65-0

Synonyms: SC40230

Bidisomide (SC40230) is an agent of class I antiarrhythmic.

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Bidisomide, CAS 116078-65-0

Pack Size	Availability	Price/USD
1 mg	In stock	$ 193.00
5 mg	In stock	$ 488.00
10 mg	In stock	$ 716.00
25 mg	In stock	$ 1,120.00
50 mg	In stock	$ 1,480.00
100 mg	In stock	$ 1,980.00
500 mg	In stock	$ 3,970.00
1 mL * 10 mM (in DMSO)	In stock	$ 538.00

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Purity: 99.56%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Bidisomide (SC40230) is an agent of class I antiarrhythmic.

In vivo

Bidisomide's anti-arrhythmia effects. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. After 5 minutes of coronary artery occlusion, the antiarrhythmic effect of 5 mg/kg Bidisomide was similar to the same dose of MXT and DSP in rats with ventricular arrhythmias caused by coronary reperfusion. All three drugs significantly slow the heart rate[1].

Synonyms	SC40230
Molecular Weight	407.98
Formula	C22H34ClN3O2
CAS No.	116078-65-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 225.0 mg/mL (551.5 mM), Sonication is recommended.

References and Literature

1. Komori S, et al. Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide. Heart Vessels. 1995;10(1):7-11.

Related compound libraries

This product is contained In the following compound libraries：

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Bidisomide 116078-65-0 Others SC 40230 SC-40230 SC40230 inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.