Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 35 days | $ 155.00 | |
10 mg | 35 days | $ 1,190.00 |
Description | Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. |
Targets&IC50 | PD-1/PD-L1:1.4 nM |
In vitro | BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay[1]. BMS-1166 dose dependently abolishes the inhibition of ECs stimulation by sPD-L1[2]. |
Molecular Weight | 677.57 |
Formula | C36H34Cl2N2O7 |
CAS No. | 2113650-05-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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